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Ion- and water-binding sites inside an occluded hourglass pore of a trimeric intracellular cation (TRIC) channel

BACKGROUND: Trimeric intracellular cation (TRIC) channels are crucial for Ca(2+) handling in eukaryotes and are involved in K(+) uptake in prokaryotes. Recent studies on the representative members of eukaryotic and prokaryotic TRIC channels demonstrated that they form homotrimeric units with the ion...

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Detalles Bibliográficos
Autores principales: Ou, Xiaomin, Guo, Jianli, Wang, Longfei, Yang, Hanting, Liu, Xiuying, Sun, Jianyuan, Liu, Zhenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401562/
https://www.ncbi.nlm.nih.gov/pubmed/28431535
http://dx.doi.org/10.1186/s12915-017-0372-8