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Peptides with 6-Aminohexanoic Acid: Synthesis and Evaluation as Plasmin Inhibitors

Fifteen new peptide derivatives of ɛ-aminocaproic acid (EACA) containing the known fragment –Ala–Phe–Lys– with an affinity for plasmin were synthesised in the present study. The synthesis was carried out a solid phase. The following compounds were synthesised: H–Phe–Lys–EACA–X, H–d-Ala–Phe–Lys–EACA–...

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Detalles Bibliográficos
Autores principales: Purwin, Maciej, Markowska, Agnieszka, Bruzgo, Irena, Rusak, Tomasz, Surażyński, Arkadiusz, Jaworowska, Urszula, Midura-Nowaczek, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401710/
https://www.ncbi.nlm.nih.gov/pubmed/28491013
http://dx.doi.org/10.1007/s10989-016-9555-3