Spatiotemporal Mapping Techniques Show Clozapine Impairs Neurogenic and Myogenic Patterns of Activity in the Colon of the Rabbit in a Dose-Dependent Manner

Background: Clozapine, an antipsychotic used in treatment-resistant schizophrenia, has adverse gastrointestinal effects with significant associated morbidity and mortality. However, its effects on defined patterns of colonic contractile activity have not been assessed. Method: We used novel radial a...

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Detalles Bibliográficos
Autores principales: Every-Palmer, Susanna, Lentle, Roger G., Reynolds, Gordon, Hulls, Corrin, Chambers, Paul, Dunn, Helen, Ellis, Pete M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401895/
https://www.ncbi.nlm.nih.gov/pubmed/28484390
http://dx.doi.org/10.3389/fphar.2017.00209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401895/
https://www.ncbi.nlm.nih.gov/pubmed/28484390
http://dx.doi.org/10.3389/fphar.2017.00209

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