Cargando…

Synthesis and anti-obesity effects in vivo of Crotadihydrofuran C as a novel PPARγ antagonist from Crotalaria albida

Crotadihydrofuran C (CC) from the herbs of Crotalaria albida is able to inhibit adipocyte differentiation and lipid accumulation. However, the effects of CC on obesity and metabolic disorders have not yet been elucidated. In our study, the first enantioselective synthesis of the 2-isopropenyl dihydr...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Qin-Hu, Zhang, Yu, Chou, Gui-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402262/
https://www.ncbi.nlm.nih.gov/pubmed/28436456
http://dx.doi.org/10.1038/srep46735