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Phosphatidylethanolamine dynamics are required for osteoclast fusion

Osteoclasts, responsible for bone resorption, are multinucleated cells formed by cell-cell fusion of mononuclear pre-osteoclasts. Although osteoclast fusion is a pivotal step for osteoclastogenesis, little is known about the mechanism involved. To clarify the underlying process, we investigated dyna...

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Detalles Bibliográficos
Autores principales: Irie, Atsushi, Yamamoto, Kei, Miki, Yoshimi, Murakami, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402267/
https://www.ncbi.nlm.nih.gov/pubmed/28436434
http://dx.doi.org/10.1038/srep46715