Dihydromyricetin Induces Apoptosis and Reverses Drug Resistance in Ovarian Cancer Cells by p53-mediated Downregulation of Survivin

Ovarian cancer is one of the leading causes of death in gynecological malignancies, and the resistance to chemotherapeutic agents remains a major challenge to successful ovarian cancer chemotherapy. Dihydromyricetin (DHM), a natural flavonoid derived from Ampeopsis Grossdentata, has been widely appl...

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Detalles Bibliográficos
Autores principales: Xu, Yingqi, Wang, Shengpeng, Chan, Hon Fai, Lu, Huaiwu, Lin, Zhongqiu, He, Chengwei, Chen, Meiwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402300/
https://www.ncbi.nlm.nih.gov/pubmed/28436480
http://dx.doi.org/10.1038/srep46060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402300/
https://www.ncbi.nlm.nih.gov/pubmed/28436480
http://dx.doi.org/10.1038/srep46060

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