Cargando…

Dihydromyricetin Induces Apoptosis and Reverses Drug Resistance in Ovarian Cancer Cells by p53-mediated Downregulation of Survivin

Ovarian cancer is one of the leading causes of death in gynecological malignancies, and the resistance to chemotherapeutic agents remains a major challenge to successful ovarian cancer chemotherapy. Dihydromyricetin (DHM), a natural flavonoid derived from Ampeopsis Grossdentata, has been widely appl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Yingqi, Wang, Shengpeng, Chan, Hon Fai, Lu, Huaiwu, Lin, Zhongqiu, He, Chengwei, Chen, Meiwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402300/ https://www.ncbi.nlm.nih.gov/pubmed/28436480 http://dx.doi.org/10.1038/srep46060

Ejemplares similares

Decitabine and SAHA-Induced Apoptosis Is Accompanied by Survivin Downregulation and Potentiated by ATRA in p53-Deficient Cells
por: Brodská, Barbora, et al.
Publicado: (2014)

Dasatinib reverses drug resistance by downregulating MDR1 and Survivin in Burkitt lymphoma cells
por: Tabata, Mitsuki, et al.
Publicado: (2020)

Noscapine Induced Apoptosis via Downregulation of Survivin in Human Neuroblastoma Cells Having Wild Type or Null p53
por: Li, Shiwang, et al.
Publicado: (2012)

Reversal Effect of Dihydromyricetin on Multiple Drug Resistance in SGC7901/5-FU Cells
por: Wu, Mingcai, et al.
Publicado: (2020)

Golgi reassembly and stacking protein 65 downregulation is required for the anti-cancer effect of dihydromyricetin on human ovarian cancer cells
por: Wang, Fengjie, et al.
Publicado: (2019)

Berbamine induces SMMC-7721 cell apoptosis via upregulating p53, downregulating survivin expression and activating mitochondria signaling pathway
por: Cao, Ying, et al.
Publicado: (2018)

Dihydromyricetin induces apoptosis and inhibits proliferation in hepatocellular carcinoma cells
por: LIU, JIE, et al.
Publicado: (2014)

Dihydromyricetin induces apoptosis in a human choriocarcinoma cell line
por: Zuo, Yanzhen, et al.
Publicado: (2018)

Mitotic Arrest and Apoptosis in Breast Cancer Cells Induced by Origanum majorana Extract: Upregulation of TNF-α and Downregulation of Survivin and Mutant p53
por: Al Dhaheri, Yusra, et al.
Publicado: (2013)

Downregulation of survivin by adenovirus-mediated shRNA promotes apoptosis in skin cancer cells
por: Hao, Yuqin, et al.
Publicado: (2019)

Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin
por: Wang, Shengpeng, et al.
Publicado: (2017)

[Retracted] Resistance to the mTOR inhibitor everolimus is reversed by the downregulation of survivin in breast cancer cells
por: Taglieri, Ludovica, et al.
Publicado: (2023)

Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells
por: Zhang, Jinming, et al.
Publicado: (2017)

Effects and mechanism of downregulation of survivin expression by RNA interference on proliferation and apoptosis of lung cancer cells
por: CHEN, XIANG-QI, et al.
Publicado: (2012)

Hydroxycamptothecin induces apoptosis and inhibits tumor growth in colon cancer by the downregulation of survivin and XIAP expression
por: Fei, Bojian, et al.
Publicado: (2013)

Intron-specific shRNA-mediated downregulation of survivin and promotion of apoptosis in HeLa cells
por: Wang, Yue-Li, et al.
Publicado: (2017)

Dihydromyricetin hexaacetate
por: Li, Wei, et al.
Publicado: (2010)

The Versatile Effects of Dihydromyricetin in Health
por: Li, Hongliang, et al.
Publicado: (2017)

Mechanism of Dihydromyricetin on Inflammatory Diseases
por: Sun, Yang, et al.
Publicado: (2022)

Dihydromyricetin promotes hepatocellular carcinoma regression via a p53 activation-dependent mechanism
por: Zhang, Qingyu, et al.
Publicado: (2014)

Dihydromyricetin Alleviates High Glucose-Induced Oxidative Stress and Apoptosis in Human Retinal Pigment Epithelial Cells by Downregulating miR-34a Expression
por: Li, Wenjun, et al.
Publicado: (2021)

P53 and survivin expression in renal cell carcinoma
por: Radovanović, Milan, et al.
Publicado: (2023)

Downregulation of survivin by siRNA inhibits invasion and promotes apoptosis in neuroblastoma SH-SY5Y cells
por: Zhang, L., et al.
Publicado: (2014)

YM155 sensitizes HeLa cells to TRAIL-mediated apoptosis via cFLIP and survivin downregulation
por: Chandrasekaran, Arun Pandian, et al.
Publicado: (2020)

Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation
por: Seo, Sung-Keum, et al.
Publicado: (2014)

Strategic developments in the drug delivery of natural product dihydromyricetin: applications, prospects, and challenges
por: Zhang, Ruirui, et al.
Publicado: (2022)

Survivin expression in ovarian cancer and its correlation with clinico-pathological, surgical and apoptosis-related parameters
por: Ferrandina, G, et al.
Publicado: (2005)

Dihydromyricetin Reduced Bcl-2 Expression via p53 in Human Hepatoma HepG2 Cells
por: Wu, Shixing, et al.
Publicado: (2013)

Dihydromyricetin inhibits African swine fever virus replication by downregulating toll-like receptor 4-dependent pyroptosis in vitro
por: Chen, Yang, et al.
Publicado: (2023)

Survivin Promotes Piperlongumine Resistance in Ovarian Cancer
por: Nan, Xing-Wei, et al.
Publicado: (2019)

Recent Update on the Pharmacological Effects and Mechanisms of Dihydromyricetin
por: Zhang, Jingyao, et al.
Publicado: (2018)

Research progress of dihydromyricetin in the treatment of diabetes mellitus
por: Wang, Ziyuan, et al.
Publicado: (2023)

Synergistic Effect of Sulindac and Simvastatin on Apoptosis in Lung Cancer A549 Cells through AKT-Dependent Downregulation of Survivin
por: Kim, Young-Suk, et al.
Publicado: (2015)

Cepharanthine Enhances TRAIL-Mediated Apoptosis Through STAMBPL1-Mediated Downregulation of Survivin Expression in Renal Carcinoma Cells
por: Shahriyar, Sk Abrar, et al.
Publicado: (2018)

Is Ovarian Preservation Feasible in Early-Stage Adenocarcinoma of the Cervix?
por: Lu, Huaiwu, et al.
Publicado: (2016)

Targeting survivin and p53 in pediatric acute lymphoblastic leukemia
por: Tyner, J W, et al.
Publicado: (2012)

Mutant p53 regulates Survivin to foster lung metastasis
por: Tang, Qiaosi, et al.
Publicado: (2021)

An otoprotective role for the apoptosis inhibitor protein survivin
por: Knauer, S K, et al.
Publicado: (2010)

Oxidative stress specifically downregulates survivin to promote breast tumour formation
por: Pervin, S, et al.
Publicado: (2013)

Dihydromyricetin Enhances the Chemo-Sensitivity of Nedaplatin via Regulation of the p53/Bcl-2 Pathway in Hepatocellular Carcinoma Cells
por: Jiang, Lianggui, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_kde4u0s4d546iqtgadotrk4709