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Drug-enhanced carbon monoxide production from heme by cytochrome P450 reductase

Carbon monoxide (CO) formed endogenously is considered to be cytoprotective, and the vast majority of CO formation is attributed to the degradation of heme by heme oxygenases-1 and -2 (HO-1, HO-2). Previously, we observed that brain microsomes containing HO-2 produced many-fold more CO in the presen...

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Detalles Bibliográficos
Autores principales: Vukomanovic, Dragic, Rahman, Mona N., Jia, Zongchao, Nakatsu, Kanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402345/
https://www.ncbi.nlm.nih.gov/pubmed/28480030
http://dx.doi.org/10.4103/2045-9912.202908