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Curcumol allosterically modulates GABA(A) receptors in a manner distinct from benzodiazepines
Inhibitory A type γ-aminobutyric acid receptors (GABA(A)Rs) play a pivotal role in orchestrating various brain functions and represent an important molecular target in neurological and psychiatric diseases, necessitating the need for the discovery and development of novel modulators. Here, we show t...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402396/ https://www.ncbi.nlm.nih.gov/pubmed/28436443 http://dx.doi.org/10.1038/srep46654 |