Malathion increases apoptotic cell death by inducing lysosomal membrane permeabilization in N2a neuroblastoma cells: a model for neurodegeneration in Alzheimer’s disease

Malathion is an organophosphate with severe neurotoxic effects. Upon acute exposure, malathion initially enhances cholinergic activity by inhibition of acetylcholinesterase, which is its major pathological mechanism. Malathion also induces non-cholinergic neuronal cell death in neurodegenerative con...

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Detalles Bibliográficos
Autores principales: Venkatesan, Ramu, Park, Yong Un, Ji, Eunhee, Yeo, Eui-Ju, Kim, Sun Yeou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402539/
https://www.ncbi.nlm.nih.gov/pubmed/28487766
http://dx.doi.org/10.1038/cddiscovery.2017.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402539/
https://www.ncbi.nlm.nih.gov/pubmed/28487766
http://dx.doi.org/10.1038/cddiscovery.2017.7

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