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Dexrazoxane for cardioprotection in older adults with acute myeloid leukemia

Anthracyclines constitute the backbone of intensive adult acute myeloid leukemia (AML) therapy. Cardiotoxicity is one of its most serious adverse effects, and its incidence increases with cumulative dose. Dexrazoxane is a cardioprotective agent used in conjunction with anthracycline therapy. There i...

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Detalles Bibliográficos
Autores principales: Vachhani, Pankit, Shin, Sarah, Baron, Jeffrey, Thompson, James E., Wetzler, Meir, Griffiths, Elizabeth A., Ontiveros, Evelena P., Spangenthal, Edward J., Wang, Eunice S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402627/
https://www.ncbi.nlm.nih.gov/pubmed/28462084
http://dx.doi.org/10.1016/j.lrr.2017.04.001