Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer’s disease model

BACKGROUND: Microglia mediate amyloid-beta peptide (Aβ)-induced neuroinflammation, which is one of the key events in the pathogenesis of Alzheimer’s disease (AD). Decoy receptor 3 (DcR3)/TNFRSF6B is a pleiotropic immunomodulator that promotes macrophage differentiation toward the M2 anti-inflammator...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Ling, Chen, Wei-Ting, Lin, Yu-Yi, Lu, Po-Hung, Hsieh, Shie-Liang, Cheng, Irene Han-Juo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402663/
https://www.ncbi.nlm.nih.gov/pubmed/28438208
http://dx.doi.org/10.1186/s13024-017-0173-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402663/
https://www.ncbi.nlm.nih.gov/pubmed/28438208
http://dx.doi.org/10.1186/s13024-017-0173-0

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