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N of 1 trials and the optimal individualisation of drug treatments: a systematic review protocol
BACKGROUND: Guidelines and evidence-based drug treatment recommendations are usually based on the results of clinical trials, which have limited generalisability in routine clinical settings due to their restrictive eligibility criteria. These trials are also conducted in ideal and rigorously contro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402671/ https://www.ncbi.nlm.nih.gov/pubmed/28438226 http://dx.doi.org/10.1186/s13643-017-0479-6 |