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Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity

A variety of xenobiotic chemicals, such as polycyclic aromatic hydrocarbons (PAHs), aryl- and heterocyclic amines and tobacco related nitrosamines, are ubiquitous environmental carcinogens and are required to be activated to chemically reactive metabolites by xenobiotic-metabolizing enzymes, includi...

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Detalles Bibliográficos
Autor principal: Shimada, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Toxicology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402866/
https://www.ncbi.nlm.nih.gov/pubmed/28443179
http://dx.doi.org/10.5487/TR.2017.33.2.079