Role of cleavage at the core-E1 junction of hepatitis C virus polyprotein in viral morphogenesis

In hepatitis C virus (HCV) polyprotein sequence, core protein terminates with E1 envelope signal peptide. Cleavage by signal peptidase (SP) separates E1 from the complete form of core protein, anchored in the endoplasmic reticulum (ER) membrane by the signal peptide. Subsequent cleavage of the signa...

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Detalles Bibliográficos
Autores principales: Pène, Véronique, Lemasson, Matthieu, Harper, Francis, Pierron, Gérard, Rosenberg, Arielle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402940/
https://www.ncbi.nlm.nih.gov/pubmed/28437468
http://dx.doi.org/10.1371/journal.pone.0175810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402940/
https://www.ncbi.nlm.nih.gov/pubmed/28437468
http://dx.doi.org/10.1371/journal.pone.0175810

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