Inhibition of α(v)β(3) integrin induces loss of cell directionality of oral squamous carcinoma cells (OSCC)

The connective tissue formed by extracellular matrix (ECM) rich in fibronectin and collagen consists a barrier that cancer cells have to overpass to reach blood vessels and then a metastatic site. Cell adhesion to fibronectin is mediated by α(v)β(3) and α(5)β(1) integrins through an RGD motif presen...

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Detalles Bibliográficos
Autores principales: Montenegro, Cyntia F., Casali, Bruna C., Lino, Rafael L. B., Pachane, Bianca C., Santos, Patty K., Horwitz, Alan R., Selistre-de-Araujo, Heloisa S., Lamers, Marcelo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402964/
https://www.ncbi.nlm.nih.gov/pubmed/28437464
http://dx.doi.org/10.1371/journal.pone.0176226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402964/
https://www.ncbi.nlm.nih.gov/pubmed/28437464
http://dx.doi.org/10.1371/journal.pone.0176226

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