Use of short interfering RNA delivered by cationic liposomes to enable efficient down-regulation of PTPN22 gene in human T lymphocytes

Type 1 diabetes and thyroid disease are T cell-dependent autoimmune endocrinopathies. The standard substitutive administration of the deficient hormones does not halt the autoimmune process; therefore, development of immunotherapies aiming to preserve the residual hormonal cells, is of crucial impor...

Descripción completa

Detalles Bibliográficos
Autores principales: Perri, Valentina, Pellegrino, Marsha, Ceccacci, Francesca, Scipioni, Anita, Petrini, Stefania, Gianchecchi, Elena, Lo Russo, Anna, De Santis, Serena, Mancini, Giovanna, Fierabracci, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402975/
https://www.ncbi.nlm.nih.gov/pubmed/28437437
http://dx.doi.org/10.1371/journal.pone.0175784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402975/
https://www.ncbi.nlm.nih.gov/pubmed/28437437
http://dx.doi.org/10.1371/journal.pone.0175784

Ejemplares similares