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Survivin downregulation using siRNA nanoliposomes inhibits cell proliferation and promotes the apoptosis of MHCC-97H hepatic cancer cells: An in vitro and in vivo study

At present, survivin is one of the most cancer-specific proteins that has been identified. The present study aimed to investigate the antitumor effects of novel survivin small interfering RNA (siRNA) nanoliposomes targeting survivin in human hepatocellular carcinoma MHCC-97H cells and xenograft mous...

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Detalles Bibliográficos
Autores principales: Liu, Ziqin, Wang, Tianyou, Zhang, Zhaoxia, Tang, Suoqin, Feng, Shunqiao, Yue, Mei, Hu, Mengze, Xuan, Litian, Chen, Yanfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403348/
https://www.ncbi.nlm.nih.gov/pubmed/28454458
http://dx.doi.org/10.3892/ol.2017.5754