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A heptameric peptide purified from Spirulina sp. gastrointestinal hydrolysate inhibits angiotensin I-converting enzyme- and angiotensin II-induced vascular dysfunction in human endothelial cells

In this study, a marine microalga Spirulina sp.-derived protein was hydrolyzed using gastrointestinal enzymes to produce an angiotensin I (Ang I)-converting enzyme (ACE) inhibitory peptide. Following consecutive purification, the potent ACE inhibitory peptide was composed of 7 amino acids, Thr-Met-G...

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Detalles Bibliográficos
Autores principales: Heo, Seong-Yeong, Ko, Seok-Chun, Kim, Chang Su, Oh, Gun-Woo, Ryu, Bomi, Qian, Zhong-Ji, Kim, Geunhyung, Park, Won Sun, Choi, Il-Whan, Phan, Thi Tuong Vy, Heo, Soo-Jin, Kang, Do-Hyung, Yi, Myunggi, Jung, Won-Kyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403476/
https://www.ncbi.nlm.nih.gov/pubmed/28393188
http://dx.doi.org/10.3892/ijmm.2017.2941