Orally administered simvastatin partially preserves lumbar vertebral bone mass but not integrity of intervertebral discs in ovariectomized rats

The present study aimed to investigate the effect of orally administered simvastatin on lumbar vertebral bone mass and intervertebral disc (IVD) degeneration in ovariectomized (OVX) rats. A total of 30 female Sprague-Dawley (SD) rats were subjected to either bilateral ovariectomy (n=20) or sham surg...

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Detalles Bibliográficos
Autores principales: Tian, Fa-Ming, Li, Shu-Yang, Yang, Kai, Luo, Yang, Dai, Mu-Wei, Liu, Guang-Yuan, Song, Hui-Ping, Zhang, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403518/
https://www.ncbi.nlm.nih.gov/pubmed/28450913
http://dx.doi.org/10.3892/etm.2017.4043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403518/
https://www.ncbi.nlm.nih.gov/pubmed/28450913
http://dx.doi.org/10.3892/etm.2017.4043

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