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Optimized construction of MUC1-VNTR(n) DNA vaccine and its anti-pancreatic cancer efficacy

Considering mucin 1-variable number tandem repeat (MUC1-VNTR(n)) as a novel target for pancreatic cancer immunotherapy, the present study aimed to screen and identify the pVAX1-MUC1-VNTR(n) DNA vaccine with the strongest immunogenicity. Following construction of a pVAX1-MUC1-VNTR(n) plasmid, immatur...

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Detalles Bibliográficos
Autores principales: Gong, Yuan-Feng, Zhou, Quan-Bo, Liao, Ya-Di, Mai, Cong, Chen, Tie-Jun, Tang, Yun-Qiang, Chen, Ru-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403551/
https://www.ncbi.nlm.nih.gov/pubmed/28454381
http://dx.doi.org/10.3892/ol.2017.5717