Cellular source and proinflammatory roles of high‐mobility group box 1 in surgically injured rat vocal folds

OBJECTIVES/HYPOTHESIS: High‐mobility group box 1 (HMGB1) is a chromatin‐binding protein located in the cell nucleus. Following injury, immunocompetent cells secrete HMGB1 to the extracellular milieu under the stimulation of proinflammatory cytokines. Extracellular HMGB1 acts a danger signal that ins...

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Detalles Bibliográficos
Autores principales: Li‐Jessen, Nicole Y. K., Powell, Michael, Choi, Ae‐Jin, Lee, Byung‐Joo, Thibeault, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Laryngology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403630/
https://www.ncbi.nlm.nih.gov/pubmed/27774594
http://dx.doi.org/10.1002/lary.26333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403630/
https://www.ncbi.nlm.nih.gov/pubmed/27774594
http://dx.doi.org/10.1002/lary.26333

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