Cargando…

miR-600 inhibits cell proliferation, migration and invasion by targeting p53 in mutant p53-expressing human colorectal cancer cell lines

Mutations of the tumor protein p53 gene, a tumor suppressor, are one of the most frequent genetic alterations observed in cancer. It has been reported that mutations in p53 result in the loss of wild-type p53 activity, and the gain of novel oncogenic properties that promote tumor growth and progress...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Peili, Zuo, Zhigui, Wu, Aihua, Shang, Wenjing, Bi, Ruichun, Jin, Qike, Wu, Jianbo, Jiang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403669/
https://www.ncbi.nlm.nih.gov/pubmed/28454325
http://dx.doi.org/10.3892/ol.2017.5654