Impact of gabapentin on neuronal high voltage-activated Ca(2+) channel properties of injured-side axotomized and adjacent uninjured dorsal root ganglions in a rat model of spinal nerve ligation

The density and properties of ion channels in the injured axon and dorsal root ganglion (DRG) neuronal soma membrane change following nerve injury, which may result in the development of neuropathic pain. Gabapentin (GBP) is a drug for the first-line treatment of neuropathic pain. One of its therape...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Minmin, Sun, Xiaodi, Chen, Xiaodong, Xiao, Hang, Duan, Manlin, Xu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403705/
https://www.ncbi.nlm.nih.gov/pubmed/28450909
http://dx.doi.org/10.3892/etm.2017.4071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403705/
https://www.ncbi.nlm.nih.gov/pubmed/28450909
http://dx.doi.org/10.3892/etm.2017.4071

Ejemplares similares