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Inhibition of CYFIP2 promotes gastric cancer cell proliferation and chemoresistance to 5-fluorouracil through activation of the Akt signaling pathway

Gastric cancer is a common gastrointestinal malignancy that accounts for a notable proportion of cancer-associated mortalities worldwide. Cytoplasmic fragile X mental retardation 1-interacting protein 2 (CYFIP2) is a novel p53-mediated pro-apoptotic protein whose expression is decreased in gastric c...

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Detalles Bibliográficos
Autores principales: Jiao, Shuhua, Li, Nuo, Cai, Shuang, Guo, Haimei, Wen, Yanhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403719/
https://www.ncbi.nlm.nih.gov/pubmed/28454373
http://dx.doi.org/10.3892/ol.2017.5743