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Therapeutic efficacy of α-radioimmunotherapy with different activity levels of the (213)Bi-labeled monoclonal antibody MX35 in an ovarian cancer model

BACKGROUND: The aim of this study was to compare the therapeutic efficacy of two different activity levels of the (213)Bi-labeled monoclonal antibody MX35 in an ovarian cancer model. Sixty female BALB/c (nu/nu) mice were inoculated intraperitoneally with human ovarian cancer cells (OVCAR-3). Two wee...

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Detalles Bibliográficos
Autores principales: Gustafsson-Lutz, Anna, Bäck, Tom, Aneheim, Emma, Hultborn, Ragnar, Palm, Stig, Jacobsson, Lars, Morgenstern, Alfred, Bruchertseifer, Frank, Albertsson, Per, Lindegren, Sture
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403775/
https://www.ncbi.nlm.nih.gov/pubmed/28439844
http://dx.doi.org/10.1186/s13550-017-0283-2