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Elamipretide (SS-31) Ameliorates Isoflurane-Induced Long-Term Impairments of Mitochondrial Morphogenesis and Cognition in Developing Rats

Mitochondria are supposed to be involved in the early pathogenesis of general anesthesia (GA)-induced neurotoxicity and long-term cognitive deficits in developing brains. However, effective pharmacologic agents targeted on mitochondria during GA exposure are lacking. This study explores the protecti...

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Detalles Bibliográficos
Autores principales: Wu, Jing, Hao, Shuangying, Sun, Xiao-Ru, Zhang, Hui, Li, Huihui, Zhao, Hongting, Ji, Mu-Huo, Yang, Jian-Jun, Li, Kuanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403826/
https://www.ncbi.nlm.nih.gov/pubmed/28487636
http://dx.doi.org/10.3389/fncel.2017.00119