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Elamipretide (SS-31) Ameliorates Isoflurane-Induced Long-Term Impairments of Mitochondrial Morphogenesis and Cognition in Developing Rats
Mitochondria are supposed to be involved in the early pathogenesis of general anesthesia (GA)-induced neurotoxicity and long-term cognitive deficits in developing brains. However, effective pharmacologic agents targeted on mitochondria during GA exposure are lacking. This study explores the protecti...
Autores principales: | Wu, Jing, Hao, Shuangying, Sun, Xiao-Ru, Zhang, Hui, Li, Huihui, Zhao, Hongting, Ji, Mu-Huo, Yang, Jian-Jun, Li, Kuanyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403826/ https://www.ncbi.nlm.nih.gov/pubmed/28487636 http://dx.doi.org/10.3389/fncel.2017.00119 |
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