Physiological and therapeutic regulation of PCSK9 activity in cardiovascular disease

Ischemic heart disease is the main cause of death worldwide and is accelerated by increased levels of low-density lipoprotein cholesterol (LDL-C). Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a potent circulating regulator of LDL-C through its ability to induce degradation of the LDL rec...

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Detalles Bibliográficos
Autores principales: Glerup, Simon, Schulz, Rainer, Laufs, Ulrich, Schlüter, Klaus-Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403857/
https://www.ncbi.nlm.nih.gov/pubmed/28439730
http://dx.doi.org/10.1007/s00395-017-0619-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403857/
https://www.ncbi.nlm.nih.gov/pubmed/28439730
http://dx.doi.org/10.1007/s00395-017-0619-0

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