The Relation Between Inflation in Type-I and Type-II Error Rate and Population Divergence in Genome-Wide Association Analysis of Multi-Ethnic Populations

Population divergence impacts the degree of population stratification in Genome Wide Association Studies. We aim to: (i) investigate type-I error rate as a function of population divergence (F(ST)) in multi-ethnic (admixed) populations; (ii) evaluate the statistical power and effect size estimates;...

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Detalles Bibliográficos
Autores principales: Derks, E. M., Zwinderman, A. H., Gamazon, E. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403879/
https://www.ncbi.nlm.nih.gov/pubmed/28185111
http://dx.doi.org/10.1007/s10519-017-9837-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403879/
https://www.ncbi.nlm.nih.gov/pubmed/28185111
http://dx.doi.org/10.1007/s10519-017-9837-3

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