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The Relation Between Inflation in Type-I and Type-II Error Rate and Population Divergence in Genome-Wide Association Analysis of Multi-Ethnic Populations
Population divergence impacts the degree of population stratification in Genome Wide Association Studies. We aim to: (i) investigate type-I error rate as a function of population divergence (F(ST)) in multi-ethnic (admixed) populations; (ii) evaluate the statistical power and effect size estimates;...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403879/ https://www.ncbi.nlm.nih.gov/pubmed/28185111 http://dx.doi.org/10.1007/s10519-017-9837-3 |