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Optogenetic Rescue of Locomotor Dysfunction and Dopaminergic Degeneration Caused by Alpha-Synuclein and EKO Genes

α-Synuclein (α-Syn) is a small presynaptic protein and its mutant forms (e.g. A53T) are known to be directly associated with Parkinson's disease (PD). Pathophysiological mechanisms underlying α-Syn-mediated neurodegeneration in PD still remain to be explored. However, several studies strongly s...

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Detalles Bibliográficos
Autores principales: Qi, Cheng, Varga, Scott, Oh, Soo-Jin, Lee, C. Justin, Lee, Daewoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403912/
https://www.ncbi.nlm.nih.gov/pubmed/28442946
http://dx.doi.org/10.5607/en.2017.26.2.97