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Regulatory T Cells and Pro-inflammatory Responses Predominate in Children with Tuberculosis

BACKGROUND: Following infection with Mycobacterium tuberculosis (M.tb), children are more susceptible to develop disease particularly extrapulmonary disease than adults. The exact mechanisms required for containment of M.tb are not known, but would be important to identify correlates of protection....

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Detalles Bibliográficos
Autores principales: Whittaker, Elizabeth, Nicol, Mark, Zar, Heather J., Kampmann, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403917/
https://www.ncbi.nlm.nih.gov/pubmed/28487695
http://dx.doi.org/10.3389/fimmu.2017.00448