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Prolonged Absence of Mechanoluminal Stimulation in Human Intestine Alters the Transcriptome and Intestinal Stem Cell Niche

BACKGROUND & AIMS: For patients with short-bowel syndrome, intestinal adaptation is required to achieve enteral independence. Although adaptation has been studied extensively in animal models, little is known about this process in human intestine. We hypothesized that analysis of matched specime...

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Detalles Bibliográficos
Autores principales: Wieck, Minna M., Schlieve, Christopher R., Thornton, Matthew E., Fowler, Kathryn L., Isani, Mubina, Grant, Christa N., Hilton, Ashley E., Hou, Xiaogang, Grubbs, Brendan H., Frey, Mark R., Grikscheit, Tracy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403975/
https://www.ncbi.nlm.nih.gov/pubmed/28462379
http://dx.doi.org/10.1016/j.jcmgh.2016.12.008