Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing

OBJECTIVE: Arcuate proopiomelanocortin (POMC) neurons are critical nodes in the control of body weight. Often characterized simply as direct targets for leptin, recent data suggest a more complex architecture. METHODS: Using single cell RNA sequencing, we have generated an atlas of gene expression i...

Descripción completa

Detalles Bibliográficos
Autores principales: Lam, Brian Y.H., Cimino, Irene, Polex-Wolf, Joseph, Nicole Kohnke, Sara, Rimmington, Debra, Iyemere, Valentine, Heeley, Nicholas, Cossetti, Chiara, Schulte, Reiner, Saraiva, Luis R., Logan, Darren W., Blouet, Clemence, O'Rahilly, Stephen, Coll, Anthony P., Yeo, Giles S.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404100/
https://www.ncbi.nlm.nih.gov/pubmed/28462073
http://dx.doi.org/10.1016/j.molmet.2017.02.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404100/
https://www.ncbi.nlm.nih.gov/pubmed/28462073
http://dx.doi.org/10.1016/j.molmet.2017.02.007

Ejemplares similares