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Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing
OBJECTIVE: Arcuate proopiomelanocortin (POMC) neurons are critical nodes in the control of body weight. Often characterized simply as direct targets for leptin, recent data suggest a more complex architecture. METHODS: Using single cell RNA sequencing, we have generated an atlas of gene expression i...
Autores principales: | Lam, Brian Y.H., Cimino, Irene, Polex-Wolf, Joseph, Nicole Kohnke, Sara, Rimmington, Debra, Iyemere, Valentine, Heeley, Nicholas, Cossetti, Chiara, Schulte, Reiner, Saraiva, Luis R., Logan, Darren W., Blouet, Clemence, O'Rahilly, Stephen, Coll, Anthony P., Yeo, Giles S.H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404100/ https://www.ncbi.nlm.nih.gov/pubmed/28462073 http://dx.doi.org/10.1016/j.molmet.2017.02.007 |
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