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Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons

OBJECTIVE: The GH/IGF-1 axis has important roles in growth and metabolism. GH and GH receptor (GHR) are active in the central nervous system (CNS) and are crucial in regulating several aspects of metabolism. In the hypothalamus, there is a high abundance of GH-responsive cells, but the role of GH si...

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Detalles Bibliográficos
Autores principales: Cady, Gillian, Landeryou, Taylor, Garratt, Michael, Kopchick, John J., Qi, Nathan, Garcia-Galiano, David, Elias, Carol F., Myers, Martin G., Miller, Richard A., Sandoval, Darleen A., Sadagurski, Marianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404104/
https://www.ncbi.nlm.nih.gov/pubmed/28462074
http://dx.doi.org/10.1016/j.molmet.2017.03.001