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Live cell imaging of mitochondria following targeted irradiation in situ reveals rapid and highly localized loss of membrane potential

The reliance of all cell types on the mitochondrial function for survival makes mitochondria an interesting target when trying to understand their role in the cellular response to ionizing radiation. By harnessing highly focused carbon ions and protons using microbeams, we have performed in situ liv...

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Detalles Bibliográficos
Autores principales: Walsh, Dietrich W. M., Siebenwirth, Christian, Greubel, Christoph, Ilicic, Katarina, Reindl, Judith, Girst, Stefanie, Muggiolu, Giovanna, Simon, Marina, Barberet, Philippe, Seznec, Hervé, Zischka, Hans, Multhoff, Gabriele, Schmid, Thomas E., Dollinger, Guenther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404225/
https://www.ncbi.nlm.nih.gov/pubmed/28440317
http://dx.doi.org/10.1038/srep46684