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Live cell imaging of mitochondria following targeted irradiation in situ reveals rapid and highly localized loss of membrane potential
The reliance of all cell types on the mitochondrial function for survival makes mitochondria an interesting target when trying to understand their role in the cellular response to ionizing radiation. By harnessing highly focused carbon ions and protons using microbeams, we have performed in situ liv...
Autores principales: | Walsh, Dietrich W. M., Siebenwirth, Christian, Greubel, Christoph, Ilicic, Katarina, Reindl, Judith, Girst, Stefanie, Muggiolu, Giovanna, Simon, Marina, Barberet, Philippe, Seznec, Hervé, Zischka, Hans, Multhoff, Gabriele, Schmid, Thomas E., Dollinger, Guenther |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404225/ https://www.ncbi.nlm.nih.gov/pubmed/28440317 http://dx.doi.org/10.1038/srep46684 |
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