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Mycobacterium tuberculosis PE_PGRS41 Enhances the Intracellular Survival of M. smegmatis within Macrophages Via Blocking Innate Immunity and Inhibition of Host Defense

The success of Mycobacterium tuberculosis (M. tuberculosis) as a pathogen is largely contributes to its ability to manipulate the host immune responses. The genome of M. tuberculosis encodes multiple immune-modulatory proteins, including several members of the multi-genic PE_PPE family. Despite of i...

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Detalles Bibliográficos
Autores principales: Deng, Wanyan, Long, Quanxin, Zeng, Jie, Li, Ping, Yang, Wenmin, Chen, Xinchun, Xie, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404228/
https://www.ncbi.nlm.nih.gov/pubmed/28440335
http://dx.doi.org/10.1038/srep46716