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Ionizing radiation abrogates the pro-tumorigenic capacity of cancer-associated fibroblasts co-implanted in xenografts

Cancer-associated fibroblasts (CAFs) are abundantly present in solid tumors and affect tumorigenesis and therapeutic responses. In the context of clinical radiotherapy, the impact of irradiated CAFs to treatment outcomes is largely unexplored. Aiming at improving radiotherapy efficacy, we have here...

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Detalles Bibliográficos
Autores principales: Grinde, Maria Tunset, Vik, Jørg, Camilio, Ketil André, Martinez-Zubiaurre, Inigo, Hellevik, Turid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404232/
https://www.ncbi.nlm.nih.gov/pubmed/28440285
http://dx.doi.org/10.1038/srep46714