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Ionizing radiation abrogates the pro-tumorigenic capacity of cancer-associated fibroblasts co-implanted in xenografts
Cancer-associated fibroblasts (CAFs) are abundantly present in solid tumors and affect tumorigenesis and therapeutic responses. In the context of clinical radiotherapy, the impact of irradiated CAFs to treatment outcomes is largely unexplored. Aiming at improving radiotherapy efficacy, we have here...
Autores principales: | Grinde, Maria Tunset, Vik, Jørg, Camilio, Ketil André, Martinez-Zubiaurre, Inigo, Hellevik, Turid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404232/ https://www.ncbi.nlm.nih.gov/pubmed/28440285 http://dx.doi.org/10.1038/srep46714 |
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