mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cells by controlling kinesin KIF13A

Mannose-6-phosphate receptor (M6PR) that facilitates cellular uptake of M6P-bearing proteins, including serine-protease granzyme-B (Gzm-B) has an important role in T-cell activation, migration and contraction. However, molecular mechanisms controlling M6PR expression in T cells remain poorly underst...

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Detalles Bibliográficos
Autores principales: Ahmed, Khawaja Ashfaque, Xiang, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404257/
https://www.ncbi.nlm.nih.gov/pubmed/28496990
http://dx.doi.org/10.1038/celldisc.2017.11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404257/
https://www.ncbi.nlm.nih.gov/pubmed/28496990
http://dx.doi.org/10.1038/celldisc.2017.11

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