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Mechanisms of antidiarrhoeal effects by diosmectite in human intestinal cells

BACKGROUND: Rotavirus (RV) induces diarrhoea through a sequence of enterotoxic and cytotoxic effects. The former are NSP4-dependent, induce calcium-dependent chloride secretion and involve oxidative stress. Diosmectite (DS) is a natural clay that has been recommended as an active therapy for diarrho...

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Detalles Bibliográficos
Autores principales: Buccigrossi, Vittoria, Russo, Carla, Guarino, Amedeo, de Freitas, Maiara Brusco, Guarino, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404323/
https://www.ncbi.nlm.nih.gov/pubmed/28450899
http://dx.doi.org/10.1186/s13099-017-0172-2