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Adverse drug reactions and kinetics of cisplatin excretion in urine of patients undergoing cisplatin chemotherapy and radiotherapy for head and neck cancer: a prospective study

BACKGROUND: Cisplatin is a high-potency anticancer agent; however, it causes significant adverse drug reactions (ADRs). Potential pharmacokinetic markers must be studied to predict or prevent cisplatin-induced ADRs and achieve better prognosis. This study was designed to investigate the relationship...

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Detalles Bibliográficos
Autores principales: Visacri, Marília Berlofa, Pincinato, Eder de Carvalho, Ferrari, Graziele Baldan, Quintanilha, Júlia Coelho França, Mazzola, Priscila Gava, Lima, Carmen Silvia Passos, Moriel, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404337/
https://www.ncbi.nlm.nih.gov/pubmed/28438219
http://dx.doi.org/10.1186/s40199-017-0178-9