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Control of an Unusual Photo-Claisen Rearrangement in Coumarin Caged Tamoxifen through an Extended Spacer

[Image: see text] The use of coumarin caged molecules has been well documented in numerous photocaging applications including for the spatiotemporal control of Cre-estrogen receptor (Cre-ERT2) recombinase activity. In this article, we report that 4-hydroxytamoxifen (4OHT) caged with coumarin via a c...

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Detalles Bibliográficos
Autores principales: Wong, Pamela T., Roberts, Edward W., Tang, Shengzhuang, Mukherjee, Jhindan, Cannon, Jayme, Nip, Alyssa J., Corbin, Kaitlin, Krummel, Matthew F., Choi, Seok Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404426/
https://www.ncbi.nlm.nih.gov/pubmed/28191924
http://dx.doi.org/10.1021/acschembio.6b00999