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Role of Hedgehog–Gli1 signaling in the enhanced proliferation and differentiation of MG63 cells enabled by hierarchical micro-/nanotextured topography

Hedgehog–Gli1 signaling is evolutionarily conserved and plays an essential role in osteoblast proliferation and differentiation as well as bone formation. To evaluate the role of the Hedgehog–Gli1 pathway in the response of osteoblasts to hierarchical biomaterial topographies, human MG63 osteoblasts...

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Detalles Bibliográficos
Autores principales: Lin, Yao, Huang, Yinghe, He, Junbing, Chen, Feng, He, Yanfang, Zhang, Wenying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404496/
https://www.ncbi.nlm.nih.gov/pubmed/28458545
http://dx.doi.org/10.2147/IJN.S135045