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In Vitro and In Vivo Activity of Omadacycline against Two Biothreat Pathogens, Bacillus anthracis and Yersinia pestis

The in vitro activity and in vivo efficacy of omadacycline (OMC) were evaluated against the causative pathogens of anthrax and plague, Bacillus anthracis and Yersinia pestis, respectively. MICs of OMC were determined by broth microdilution according to CLSI guidelines for 30 isolates each of Y. pest...

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Detalles Bibliográficos
Autores principales: Steenbergen, Judith, Tanaka, S. Ken, Miller, Lynda L., Halasohoris, Stephanie A., Hershfield, Jeremy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404541/
https://www.ncbi.nlm.nih.gov/pubmed/28223382
http://dx.doi.org/10.1128/AAC.02434-16