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Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration
BACKGROUND: Chemokine signalling is required for the homing of leukocytes during retinal inflammation, and is associated with pathogenesis of diseases such as age-related macular degeneration (AMD). Here, we explore the role of interleukin-1β (IL-1β) in modulating AMD-associated chemokines Ccl2, Cxc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404662/ https://www.ncbi.nlm.nih.gov/pubmed/28438165 http://dx.doi.org/10.1186/s13024-017-0175-y |