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Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration

BACKGROUND: Chemokine signalling is required for the homing of leukocytes during retinal inflammation, and is associated with pathogenesis of diseases such as age-related macular degeneration (AMD). Here, we explore the role of interleukin-1β (IL-1β) in modulating AMD-associated chemokines Ccl2, Cxc...

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Detalles Bibliográficos
Autores principales:	Natoli, Riccardo, Fernando, Nilisha, Madigan, Michele, Chu-Tan, Joshua A., Valter, Krisztina, Provis, Jan, Rutar, Matt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404662/ https://www.ncbi.nlm.nih.gov/pubmed/28438165 http://dx.doi.org/10.1186/s13024-017-0175-y

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